Character:White to Off-White Cyrstalline Solid.
Usage:Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
Production Capacity:5000 kg/ month
Package:1kg/bag,5kg/bag,1kg Sterile Aluminum Foil Bag, 25kg/ drum or according to your requirements.
Categories:Active Pharmaceutical Ingredients;Cnbio;Erectile Dysfunction;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's.
Delivery time:Parcel can be sent out within 24hours after your payment,4~7 days to arrive.
Avanafil is a potent,highly selective phosphodiesterase 5 inhibitor,in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than. The compound dear compliance weak against other phosphodiesterase,and effect of adenosine receptor decreased,suggesbagg that the cardiovascular effects of avanafil should be weaker than .
Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover,avanafil inhibition of phosphodiesterase 6 is very weak,the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27,2012 and by EMA on June 21,2013. Avanafil acts by inhibibagg a specific phosphodiesterase type 5 enzyme which is found in various body tissues,but primarily in the corpus cavernosum penis,as well as the rebaga. Other similar drugs are ,tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly,reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.
The common side effects are usually mild and last a few hours,and may include facial flushing,an upset stomach,and headaches. Less common side effects are blurred vision,or perceiving a bluish bagt in one's vision,and sensitivity to light.
Most side effects experienced from taking these drugs are temporary. Clinical studies have revealed that the frequency of these side effects decreases over time. However,a rare side effect,vision loss,has been reported with people who have used PDE5 inhibitors. This loss of vision could be permanent and thus any vision-related side effects require an immediate visit to a doctor or medical facility. There is no evidence as yet that PDE5 inhibitors are the direct cause of vision loss.
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